Cancer immunotherapy is the use of the immune system to treat the cancer.
Immunotherapy has been reported by doctors to have given good results against cervical cancer.
Immunotherapy carried out for 22 months helped Aricca Wallace of Bethesda in US.
Wallace is the first person with cervical cancer. For over 3 years she has suffered cramping and irregular bleeding, doctors thought it was a side effect of her birth control implant, known as an intrauterine device or IUD.
Wallace's doctor told her about an immunotherapy trial at the National Institutes of Health Clinical Center, a research hospital outside the US capital.
Doctors removed one of her tumours and collected some of the immune cells that were surrounding it. They selected specific T-cells that would attack human papillomavirus.
One of the women belonged to Manhattan, Kansas, west of Topeka. Her cancer was discovered in 2011 when she was 35-year-old. The tumor spread widely in the woman's body and one tumor grew so large that it blocked half of her windpipe.
They applied chemotherapy and radiation but failed to treat the women. They said that the women will not survive more than a year.
Wallace first endured a weeklong regimen of strong chemotherapy to knock out her immune system. Then the infusion aimed to rebuild her defences with over 100bn of her lab-grown T-cells targeting tumours. She got two doses of aldesleukin, to help immune cells grow. The treatment can lead to side effects like bleeding, vomiting, low blood pressure, fluid retention, confusion, fever and infection.
Immunotherapy has been reported by doctors to have given good results against cervical cancer.
Immunotherapy carried out for 22 months helped Aricca Wallace of Bethesda in US.
Wallace is the first person with cervical cancer. For over 3 years she has suffered cramping and irregular bleeding, doctors thought it was a side effect of her birth control implant, known as an intrauterine device or IUD.Wallace's doctor told her about an immunotherapy trial at the National Institutes of Health Clinical Center, a research hospital outside the US capital.
Doctors removed one of her tumours and collected some of the immune cells that were surrounding it. They selected specific T-cells that would attack human papillomavirus.
One of the women belonged to Manhattan, Kansas, west of Topeka. Her cancer was discovered in 2011 when she was 35-year-old. The tumor spread widely in the woman's body and one tumor grew so large that it blocked half of her windpipe.
They applied chemotherapy and radiation but failed to treat the women. They said that the women will not survive more than a year.
Wallace first endured a weeklong regimen of strong chemotherapy to knock out her immune system. Then the infusion aimed to rebuild her defences with over 100bn of her lab-grown T-cells targeting tumours. She got two doses of aldesleukin, to help immune cells grow. The treatment can lead to side effects like bleeding, vomiting, low blood pressure, fluid retention, confusion, fever and infection.
Treatment of cervical cancer depends on:
- The stage of the cancer
- The size and shape of the tumor
- The woman's age and general health
- Her desire to have children in the future Study leader, Dr. Christian Hinrichs of the Cancer Institute, assistant clinical investigator at the National Cancer Institute. "All we know is that it can work," she said.
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